PCP provides a forum for the review and publication of reports of original research in a broad range of subjects in biophysics, biochemistry and cellular physiology. Reports of direct applications of basic knowledge to human studies are invited; examples would include the measurements of relaxation times as part of NMR imaging. Single experiments, conclusions based on inadequate statistics, purely speculative papers, and clinical case reports are not accepted.
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Volume
39, Number 1, 2006 (PDF)
Complete Journal
PLCHB4 39(1) 1-110 (2007)
ISSN 0748-6642
- History of the Membrane (Pump) Theory of the Living Cell from Its
Beginning in
Mid-19th Century to Its Disproof 45 Years Ago — though Still Taught Worldwide Today as Established Truth - Regulation of 5-Aminolevulinic Aciddependent Protoporphyrin IX Accumulations in Human Histiocytic Lymphoma U937 Cells
- Exposure to an Additional Alternating Magnetic Field Affects Comb Building by Worker Hornets
- An Unanswered 2003 Letter Appealing on Behalf of all Mankind to Nobel Laureate Roderick McKinnon to Use His Newfound Fame and Visibility to Begin Restoring Honesty and Integrity to Basic Biomedical Science by Rebutting or Correcting Suspected Plagiarism in His Nobel-Prize-Winning Work
- Identical Twins, Asymmetrical Mitosis and Bilateral Symmetry of Organisms
Volume 38, Number 2, 2006 (PDF)
Complete Journal
PLCHB4 38(2) 77-158 (2006)
ISSN 0748-6642
- Effects of Acetaminophen on Hepatic Gene Expression in Mice
- Basic Study on Biochemical Mechanism of Thoron and Thermal Therapy
- Tissue Magnesium Loss during Prolonged Hypokinesia in Magnesium Supplemented and Unsupplemented Rats
- An Ultra Simple Model of Protoplasm to Test the Theory of Its Long-range Coherence and Control So Far Tested (and Affirmed) Mostly on Intact Cell(s)
- APPENDIX I-The Model of the Biological Fixed-Charge System (Reproduced from Chapter 4 of Ling, 1962)
Volume
38, Number 1, 2006 (PDF) Complete Journal
PLCHB4 38(1) 1-76 (2006)
ISSN 0748-6642
- Stimulation of Membrane Permeability Transition by a-Lipoic Acid
and its
Biochemical Characteristics - Histological Changes in Spleens of Radio-sensitive and Radio-resistant
Mice
Exposed to Low-dose X-ray Irradiation - Diazepam Inhibits Reproduction and Reproductive Behavior of Oriental
Hornet.
A Possible Role for the Peripheral-Type Benzodiazepine Receptor - MRI of Oriental Hornet Head
- In Response to an Open Invitation
for Comments on AAAS Project 2061’s
Benchmark Books on Science
Gilbert Ling
Volume 37,
Number 2, 2005 (PDF) Complete
Journal
PLCHB4 37(2) 89-161 (2006)
ISSN 0748-6642
- Mechanisms of Telomerase Binding to Telomeres
- Effects of Post Low-dose X-ray Irradiation on Carbon Tetrachloride-induced Acatalasemic Mice Liver Damage
- Water And Electrolyte Changes in Skeletal and Cardiac Muscles of Rats During Prolonged Hypokinesia
- What Befalls the Proteins and Water in a Living Cell When the Cell Dies?
Volume
37, Number 1, 2005 (PDF) Complete Journal
PLCHB4 37(1) 1-88 (2005)
ISSN 0748-6642
- An Updated and Further Developed Theory and Evidence for the Close-contact, One-on-one Association of Nearly All Cell K+ with ß- and γ-Carboxyl Groups of Intracellular Proteins
- Studies on the Amount of Aluminum and Calcium in Urine following Aluminum Administration with and without Amino Acids
- Electrical Properties of Hornet Silk: Temperature Dependence
- BOOK REVIEW: Bioelectromagnetic Medicine
Volume 36, Number 2, 2004
(PDF) Complete Journal
PLCHB4 36(1) 85-160 (2004)
ISSN 0748-6642
- Molecular Properties and Antibacterial Activity of the Methyl and Ethyl Ester Derivatives of Ampicillin
- Role of α-Tocopherol in the Regulation of Mitochondrial Permeability Transition
- Phosphate Deposition During and After Hypokinesia in Phosphate Supplemented and Unsupplemented Rats
- Temperature Distribution and Electrical Properties Along the Oriental Hornet Body
- Communication by Electrical Means in Social Insects
- How Much Water Is Made “Non-free” by 36% Native Hemoglobin?
Volume
36, Number 1, 2004 (PDF) Complete Journal
PLCHB4 36(1) 1-88 (2004)
ISSN 0748-6642
- What Determines the Normal Water Content of a Living Cell?
- 17ß-Estradiol Suppresses ROS-induced Apoptosis of CHO Cells through Inhibition of Lipid Peroxidation-coupled Membrane Permeability Transition
- Evaluation of a Simple Carrier Molecule to Enhance Drug Penetration
of Dermal Layers by Utilizing Multivariate Methods,
Structure Property Correlations, and Continuous System Modeling - The Thermoelectric Properties of Hornet Cuticle: Correlation With Measuring Body Sites and Activity Status
- On the Modulation Effect of Pulsing and Static Magnetic Fields and Mechanical Vibrations on Barley Seed Hydration
Volume 35, Number 2, 2003
(PDF) Complete Journal
PLCHB4 35(2) 91-171 (2003)
ISSN 0748-6642
- A New Theoretical Foundation for the Polarized-Oriented Multilayer Theory of Cell Water and for Inanimate Systems Demonstrating Long-range Dynamic Structuring of Water Molecules
- Cepharanthine, an Anti-inflammatory Drug, Suppresses Mitochondrial Membrane Permeability Transition
- MR Imaging of Vertebral Metastases at 0.2 Tesla: Clinical Evaluation of T1-weighted Opposed-phase Gradient-echo Imaging
- Photo-Induced Arousal Response by Hornets
Volume 35,
Number 1, 2003 (PDF) Complete Journal
PLCHB4 35(1) 1-90 (2003)
ISSN 0748-6642
- Effect of Endogenously Generated Nitric Oxide on the Energy Metabolism of Peritoneal Macrophages
- Spectral Properties of Adrenaline in Micellar Environment
- Melanocytes: Morphological Basis for anExteroceptive Sensory System
for
Monitoring Ultraviolet Radiation - Insulin Secretion in Monosodium Glutamate (MSG) Obese Rats Submitted to Aerobic Exercise Training
- MRS Study of the Interaction of Dihydropyridines with Lipid Molecules in Phosphatidylcholine Vesicles
- The Thermo-Photoelectric (TPE) Properties of the Hornet Cuticle: Correlation with the Morphological Structure
Volume 29, Number 2, 1997
PLCHB4 29(2) 123-262 (1979)
ISSN 0748-6642
- Debunking the Alleged Resurrection of the Sodium Pump Hypothesis
- Lanthionine Ketimine and S-(2-aminoethyl)-L-cysteine Ketimine Induce the Tyrosyl Phosphorylation of 45 kDa Protein in Parallel with its Stimulation of Superoxide Generation in Human Neutrophils
- Thermoregulation of the Extraretinal Photoreceptor Apparatus in the Yellow Stripes of the Gaster of Hornets
- II. Electric Energy Transfer in Hornet Silk Caps: A Qualitative Approach to the Dynamics of Charge Release
- Electrolyte Concentration in Skeletal Muscles and Plasma of Rats During and After Exposure to Hypokinesia and Hyperhydration
- A Quantitative Theory of Solute
Distribution in Cell Water According to Molecular Size.
Gilbert N. Ling - Predictions of Polarized Multilayer
Theory of Solute Distribution Confirmed from a Study of the Equilibrium
Distribution in Frog Muscle of Twenty-one Nonelectrolytes Including
Five Cryoprotectants
Gilbert N. Ling, Zeling Niu and Margaret Ochsenfeld
- Low Paramagnetic-Ion Content in Cancer Cells: Its Significance in
Cancer Detection by Magnetic Resonance Imaging
Gilbert N. Ling, Thea Kolebic and Raymond Damadian
- Partial Preservation Of The Ability Of Accumulating Alkali-Metal
Ions In 2 mm Muscle Cell Segments With Both Ends Open
Gilbert N. Ling - Further Studies On The Role of Paramagnetic Ion Contents on The NMR
Relaxation Time, T1 Of Normal Tissues And Cancer Cells
Gilbert N. Ling - The Physical State of Water in Living
Cells and Model Systems. XII. The Influence of the Conformation of a
Protein on the Solubility of Na+ (Sulfate), Sucrose, Glycine
and Urea in the Water in Which the Protein is Also Dissolved
Gilbert N. Ling and Margaret Ochsenfeld
- An Electronic Mechanism in The Action of Drugs, ATP, Transmitters
and Other Cardinal Adsorbents. II. Effect Of Ouabain on The Relative
Affinities For Li+, Na+, K+, And Rb+ Of
Surface Anionic Sites That Mediate The Entry Of Cs+ Into Frog Ovarian
Eggs
Gilbert N. Ling and Yazhen Fu - Studies on The Physical State of
Water in Living Cells and Model Systems: IX. Theoretical Significance
of a Straight Line Relationship Between Intracellular Concentration
of a Partially Excluded Solute and its Concentration in The Bathing
Medium
Gilbert N. Ling - Studies on the Physical State
of Water in Living Cells and Model Systems. X. The Dependence of
the Equilibrium
Distribution Coefficient of a Solute in Polarized Water On the Molecular
Weights of the Solute: Experimental Confirmation of the “Size
Rule” in Model Studies
Gilbert N. Ling and W. Hu - Studies on The Physical State of Water in Living Cells and Model
Systems. XI. The Equilibrium Distribution Coefficients of Pentoses
in Muscle Cell Water: Their
Dependence Primarily on The Molecular Weights of The Pentoses and Lesser Dependence on Their Stereospecificity
G. N. Ling and M. M. Ochsenfeld
- Cell Volumes And Water Contents Of Frog Muscles In Solutions Of Permeant
Sugars And Sugar Alcohols
Gilbert N. Ling - Studies On The Physical State Of Water In Living Cells and Model
Systems. VI. Concentration-Dependent Sustained Volume Changes of Dialysis
Sacs Containing Aqueous Solution of Native and Denatured Protein, Gelatin,
And Oxygen-Containing Polymers Immersed in Solutions of
Na Salt and of Sugar and Sugar Alcohol
G. N. Ling and M. M. Ochsenfeld - Studies on The Physical State of
Water in Living Cells and Model Systems. VII. Exclusion of Sugars
and Sugar Alcohols From The Water
in Sulfonate Ion Exchange Resins: The "Size Rule"
Gilbert N. Ling - On The Large Error Introduced in
The Estimate of The Density of Membrane Pores From Permeability Measurements
When Diffusion in "Unstirred
Layer" Within The Cells is Disregarded
Gilbert N. Ling - An Electronic Mechanism in The
Actions of Drugs And Other Cardinal Adsorbents. I. Effect of Ouabain
on The Relative Affinities of The
Cell Surface ß- and γ-Carboxyl Groups For K+, Na+, Glycine And Other Ions
Gilbert N. Ling and Yazhen Fu - Studies on The Physical State of Water in Living Cells and Model
Systems. VIII. Water Vapor Sorption on Proteins and Oxygen-Containing
Polymers at Physiological Vapor Pressures: Presenting a New Method
For The Study of Vapor Sorption At Close To And Including Saturation
G. N. Ling and W. X. Hu
- The Role Of Inductive Effect In The
Determination Of Protein Structure
Gilbert N. Ling - Membrane Lipid Layers Vs. Polarized Water
Dominated by Fixed Ions: A Comparative Study of the Effects of Three
Macrocyclic Ionophores on the K+ Permeability of Frog Skeletal
Muscle, Frog Ovarian Eggs, and Human Erythro-cytes
G. N. Ling and M. M. Ochsenfeld - Cooperative Interaction Among Surface ß- and γ-Carboxyl
Groups Mediating The Permeation of Ions Into Frog Muscle Cells
Gilbert N. Ling - A New Theory of The Water Contents of Living Cells in Solutions Containing
Different Concentrations of Permeant Solutes
Gilbert N. Ling - Are The Proteins in Malignant Cancer Cells Of Diverse Origin Similar
or Different?
G. N. Ling, C. Reid, and R. C. Murphy
- A Study of Selective Adsorption
of Na+ and Other Alkali-Metal Ions on Isolated Proteins: A Test of
the Salt-Linkage
Hypothesis
G. N. Ling and Z. L. Zhang - Counterarguments Against Alleged Proof Of The Na-K Pump In Studies
Of K+ and Na+ Distributions In Amphibian Eggs
Gilbert N. Ling - Quantitative Relationships Between The Concentration Of Proteins
And The Concentration Of K+ And Na+ In Red Cell Ghosts
Gilbert N. Ling, Dolores Zodda, and Mark Sellers - Effects of Adrenaline, Calcium, and Ouabain on The Resting Potential
of Frog Muscle: Interpretation Based on The Theory of Allosteric Control
of Cooperative Interactions Among Surface Anionic Sites
Gilbert N. Ling, John D. Baxter, and Michael I. Leitman - Warming-Induced Hyperpolarization of Cardiac Muscle Cells And Snail
Neurones: Interpretation Based on Temperature Transition of Cooperatively
Linked Surface
Anionic Sites Between K+ and Na+ Adsorbing States
Gilbert N. Ling - The Electron-Donating Strengths of Side Chains in the Determination
of Protein Structure
Gilbert N. Ling
- Studies On The Physical
State Of Water In Living Cells And Model Systems. I. The Quantitative
Relationship Between The Concentration
Of Gelatin And Certain Oxygen- Containing Polymers And Their Influence
Upon The Solubility Of Water For Na+ Salts
G. N. Ling and M. M. Ochsenfeld - Studies On The Physical State Of Water In Living Cells And Model
Systems. II. NMR Relaxation Times Of Water Protons In Aqueous Solutions
Of Gelatin And Oxygen-Containing Polymers Which Reduce The Solvency
Of Water For Na+, Sugars, And Free Amino Acids
G. N. Ling and R. C. Murphy - Studies On The Physical State Of Water In Living Cells And Model
Systems. 111. The High Osmotic Activities Of Aqueous Solutions Of Gelatin,
Polyvinylpyrrolidone And Poly (Ethylene Oxide) And Their Relation To
The Reduced Solubility For Na+, Sugars, And Free Amino Acids.
Gilbert N. Ling - Cold Injury-Induced Swelling Of Brain And Other Tissues: Its Molecular
Mechanism
Gilbert N. Ling and Young Kwon - Evidence That Na+ In
A Sulfonate Ion Exchange Resin Exists In An Adsorbed State. Its Significance
For The Interpretation Of Nmr
Data
In Resins And Cells
G. N. Ling and Z. L Zhang - Only Solid Red Blood Cell Ghosts Transport K+ And Na+ Against
Concentration Gradients: Hollow Intact Ghosts With K+ -
Na+ Activated Atpase Do Not
G. N. Ling and M. Tucker - Cooperative Interaction Among Cell Surface Sites: Evidence In Support
Of The Surface Adsorption Theory Of Cellular Electrical Potentials
Gilbert N. Ling and Andrew Fisher - Indifference Of The Resting Potential Of Frog Muscle Cells To External
Mg++ In The Face Of High Mg++ Permeability
Gilbert N. Ling, Cheryl L. Walton, and Margaret M. Ochsenfeld - Studies on The Physical State of Water in Living Cells and Model
Systems.
IV. Freezing And Thawing Point Depression of Water by Gelatin, Oxygen-Containing Polymers and Urea-Denatured Proteins.
G. N. Ling and Z. L. Zhang - Studies On The Physical State Of Water In Living Cells And Model
Systems.
V. The Warming Exothermic Reaction Of Frozen Aqueous Solution Of Polyvinylpyrrolidone, Poly(Ethylene Oxide), And Urea-Denatured Proteins
Z. L. Zhang and G. N. Ling - Evidence For a Significant Role of Paramagnetic Ions in the Observed
NMR Relaxation Rates of Living Tissues
Gilbert N. Ling
- The Cellular Resting And Action Potentials: Interpretation Based
On The Association-Induction Hypothesis
Gilbert N. Ling - NMR Relaxation Of Water Protons Under The Influence Of Proteins And
Other Linear Polymers
Gilbert N. Ling and R. C. Murphy - Preliminary Note
Apparent Similarity In Protein Compositions Of Maximally Deviated Cancer Cells
Gilbert N. Ling and R. C. Murphy
- Oxidative Phosphorylation And Mitochondrial Physiology: A Critical
Review Of Chemiosmotic Theory, And Reinterpretation By The Association-Induction
Hypothesis
Gilbert N. Ling - Active Solute Transport Across Frog Skin And Epithelial Cell Systems
According To The Association-Induction Hypothesis
Gilbert N. Ling - Synchronous Control Of Metabolic Activity By K+ Transiently And Reversibly
Liberated From Adsorption Sites During Muscle Contraction: An Extension
Of Association-Induction Theory
Gilbert N. Ling
- Mechanism of Solute Exclusions From Cells: The Role of Protein-Water
Interaction
Gilbert N. Ling, Margaret M. Ochsenfeld, Cheryl Walton, T. Janine Bersinger - Reduced Solubility Of Polymer-Oriented Water For Sodium Salts, Sugars,
Amino Acids, And Other Solutes Normally Maintained At Low Levels In
Living Cells
Gilbert N. Ling, Cheryl Walton, And T. Janine Bersinger - Underestimation Of Na Permeability In Muscle Cells: Implications
For The Theory Of Cell Potential And For Energy Requirement Of The
Na Pump
Gilbert N. Ling - The Role Of Multilayer Polarization Of Cell Water In The Swelling
And Shrinkage Of Living Cells
Gilbert N. Ling
- Experimental Confirmation,
From Model Studies, of a Key Prediction of the Polarized Multilayer
Theory of Cell Water.
Gilbert N. ling, Margaret M. Ochsenfeld, Cheryl Walton, T. Janine Bersinger - Peer Review and the Progress of Scientific Research
Gilbert N. Ling - How Does Reduced External K+ Concentration Affect the Rate of Na+ Efflux? Evidence Against the K-Na Coupled Pump But in Support of the Association-Induction Hypothesis
- Thallium and Cesium in Muscle Cells Compete For The Adsorption Sites
Normally Occupled By K+
Gilbert N. Ling - The Functions Of Polarized Water And Membrane Lipids: A Rebuttal
Gilbert N. Ling - K+ Localization in Muscle Cells By Autoradiography, and
Identification of K+ Adsorbing Sites in Living Muscle Cells With Uranium
Binding Sites
in Electron Micrographs of Fixed Cell Preparations
Gilbert N. Ling - Confirmation of "Universality Rule" in
Solute Distributions: Studies of Simultaneous Efflux of Na+ and D-Arabinose From Single Frog
Eggs Living, Dying, and Dead
Gilbert N. Ling and Margaret M. Ochsenfeld - Experimental Verification of an Expected Relation Between Time of
Incubation and Magnitude of The Fast and Slow Fractions of The Sodium
Efflux From Amphibian Eggs
Gilbert N. Ling and Margaret M. Ochsenfeld
- Studies On Insulin Action V. Structural Requirements Of Primers For
Subsequent
Accumulation Of D-Glucose at O°C in Insulinized Frog Muscles
Gilbert N. Ling and Sandra Will - Na+ and K+ Levels in Living Cells: Do
They Depend on The Rate of Outward Transport of Na+?
Gilbert N. Ling and Margaret M. Ochsenfeld
- The Mechanism Of Cellular Resting Potential According to The Association-Induction
Hypothesis and The Perfused Squid Axon: Correcting a Misrepresentation
Gilbert N. Ling - A Simple. Rapid Method For The Quantitative Separation of The Extracellular
Fluid in Frog Muscles
Gilbert N. Ling and Cheryl L. Walton - The Mechanism For The Exclusion Of Sugars From The Water in a Model
of The Living Cell: The Ion-Exchange Resin: Pore Size Or Water Structure?
G. N. Ling and A.M.Sobel - Simultaneous Efflux Of K+ and
Na+ From Frog
Sartorius Muscle Freed of Extracellular Fluids: Evidence For Rapidly
Exchanging
Na+ From
The Cells
Gilbert N. Ling and Cheryl L. Walton
- Exchange of 3HH0
in Intact Isolated Muscle Fiber of The Giant Barnacle
Ignacio L. Reisin and Gilbert N. Ling - How Does Ouabain Control The Levels Of Cell K+ and Na+?
By Interference With a Na Pump or By Allosteric Control of K+-Na+
Adsorption on Cytoplasmic
Protein
Sites?
Gilbert N. Ling
- Studies Of Ion Permeability. III. Diffusion of Br+ Ion
in The Extracellular Space Of Frog Muscles
Gilbert N. Ling - Studies On Ion Permeability: IV. The Mechanism Of Ouabain Action
On The Na+ -Ion Efflux In Frog Muscles
Gilbert N. Ling And Lawrence G. Palmer
- Studies On Ion Distribution In Living Cells: III. Cooperative Control
Of Electrolyte Accumulation By Ouabain In The Frog Muscle
Gilbert N. Ling and Grace F. Bohr - Studies of Ionic Distribution in Living Cells: IV. Effect of Ouabain
on The Equilibrium Concentrations Of Cs+, Rb+,
K+, Na+ and Li+ Ions
In Frog Muscle Cells
G. N. Ling and G . Bohr
- The Physical State of Water in Frog Muscles
Gilbert N. Ling and William Negendank - Demonstration of Saturability and Competition in Ion Transport Into
a Membraneless Protein-Water System
Gilbert N. Ling and Margaret M. Ochsenfeld - Studies On Ion Permeability. I. What Determines The Rate Of Na+ Ion
Efflux From Frog Muscle Cells?
Gilbert N. Ling - Structural Change of Intracellular Water In Caffeine-Contracted
Muscle Cells
Christopher Miller and Gilbert N. Ling - Studies On Ion Permeability. II. Does Exchange Diffusion Make a Significant
Contribution to The Na+ -Ion
Efflux in Frog Muscles?
Gilbert N. Ling And Ellen Ferguson
- Studies On Insulin
Action. I . The Steady Level Of Glucose Accumulation In Insulin-Treated
Frog Muscle At O° C.
Gilbert N. Ling, Margaret C. Neville, Patricia Shannon And Sandra Will - Studies On Insulin Action. II. The Extracellular Space of Frog Muscle:
Demonstration of D-Mannitol and Sucrose Entry into Isolated Single
Muscle Fibers and Intact Muscles.
Gilbert N. Ling, Margaret C. Neville, Sandra Will and Patricia Shannon - Studies on Insulin Action. III.
Linear Distribtuion of d-glucose, d-ribose and Methanol in Frog Muscle
Cells at 0°C in the Absence
of Insulin.
Gilbert N. Ling and Sandra Will - Studies On Insulin Action.
IV. Cooperative Transition In Adsorption: A Theoretical Interpretation
of The Priming Action of Glucose Treatment
At 25°C on The Subsequent Accumulation of Labeled Glucose by Insulinized
Frog
Muscle at O°C With a Discussion of Bacterial Permease Induction.
Gilbert N. Ling, Sandra Will, and Patricia Shannon - Studies On Ionic Distribution In Living Cells I. Long-Term Preservation
Of Isolated Frog Muscles
Gilbert N. Ling and Grace Bohr
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